Hormone Suppression

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5 Comments

Comment by Patricia Suarez on June 24, 2008 at 5:35pm

My husband is 71 years old and had 35 weeks of radiation therapy after laparoscopic surgery. After radiation therapy the radiologist recommended one year monthly injections of Treslstar Depot. After 5 months of injections my son and I noticed a marked decrease in his mental ability. When driving he gets lost often. One day he will tell you something and the next day he changes the story completely. His short term memory is poor. Sometimes he can remember events but other times he has no recall. The sad thing is that he becomes angry when it is brought to his attention and if he knew I was writing this on a public website he would be livid. I am in a quandary, not knowing whether it can be a result of the Trelstar injections or if it can be the onset of dementia. Has anyone experienced something similar? Thank you, Patricia

Comment by Richard on June 21, 2008 at 11:07am

My wife has been prescribed Clonodine for her hot flashes associated with menopause and it seems to help her. Not sure if it might work for ADT patients also.

Comment by Philip Balis on June 16, 2008 at 10:46am

I have aggressive PCa and am on ADT, with hot flashes, quite naturally. Has anyone tried transdermal estrogen (or other estrogen like compounds) to alleviate hot flashes? If so what was your experience.

Phil

Comment by Steve J on May 6, 2008 at 3:10pm

Here is a link to the latest Clinical Practice Guidelines from the American College of Physicians on screening men for osteoporosis: http://www.annals.org/cgi/content/full/148/9/680

This is important for us geezers, and especially for those of us on androgen deprivation therapy (ADT).

One essential quotation:

"Androgen deprivation therapy (pharmacologic and orchiectomy) is a strong predictor of both osteoporosis and fracture."

And bisphosphonates still appear to be the treatment of choice for prevention.

Comment by Steve J on April 19, 2008 at 11:41pm

No one should be forced to cope alone with the side effects (SEs) of "hormone therapy," better called androgen deprivation therapy (ADT). It is the duty of his medic to know about them and to help the patient.

Here are two excellent papers:

http://www.prostate-cancer.org/education/andind/Guess_TestosteroneSideEffects.html
or
http://tinyurl.com/2ymb8f

and

http://www.prostate-cancer.org/education/sidefx/Strum_ADS.html
or
http://tinyurl.com/g6fzp