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Ralph Valle replied to the discussion Active surveillance 1 day ago
Ralph Valle replied to the discussion Active surveillance 1 day ago
Ralph Valle replied to the discussion Active surveillance Jul 1
Ralph Valle replied to the discussion Active surveillance Jul 1
Ralph Valle replied to the discussion Active surveillance Jul 1
Ralph Valle replied to the discussion Active surveillance Jul 1
Ralph Valle replied to the discussion Prostate Cancer Epidemiology in Africa Jul 1
Ralph Valle replied to the discussion Kegels...do they really make much difference? Jun 30

Profile

Have you been diagnosed with prostate cancer?
yes
About Me:
Phoenix, Arizona. Retired chemist; PCa survivor since 1992; patient advocate; Chapter Leader for two AZ US TOO support groups; Amateur radio (KT7P); Photography.

In April 1992, I was like most of my male contemporaries, totally oblivious of prostate cancer or its significance. I had just experienced an episode of frequent nocturnal urination, which I attributed to an infection. Then out of the blue, I was tested for PSA (my very first one) and scheduled for a biopsy when this result came back abnormally high at 13.6 ng/ml

The positive diagnostic result hit me hard as all these events developed rapidly and I was dreadfully unprepared to deal with the disease. This lack of basic knowledge about prostate cancer risk as we age is one of the things that present day males must avoid. Any male can be diagnosed with prostate cancer. Many without a symptom whatsoever! Learn the basics and avoid facing a situation like I did, where I needed to depend on other's opinions to decide what to do. Treatments affect our lives. Learn and decide from a knowledge base. You owe it to yourself and your family.

Dx: 5/92 at age 58, PSA 13.6 ng/ml(first PSA ever), Gleason 5 (3,2), 6 out of 6 positive biopsy cores, T2c, DRE +, Neg. Bone scan, Neg. CT scan, Neg. bladder pyelogram, Neg. chest x-ray,

Tx: RP 6/92, Gleason 6 (4,2), T4, Bilateral seminal vesicle invasion, positive margins, tumor invading and attached to rectum wall, Bilateral orchiectomy 9/92, PSA <0.2 ng/ml since 9/92;PSA 9/05, <0.03 ng/ml, DPC assay; PSA 3/06, <0.1 ng/ml, Abbott; Last PSA 3/07, <0.1 ng/ml, Bayer assay; 5/08, <0.1 ng/ml, Roche
Website:
http://www.pcainaz.org

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Comment Wall (22 comments)

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At 12:13am on June 26th, 2008, edward roge said…
Hi Ralph
As you know Dr Berger retired. I am currently being treated by his Physician's Asst, who I find very kmowledgeable and competent. In my position with a failed rp (1996) and rising psa, cuurently about 1.25, I am thinking about suggesting to the PA some form of aggressive treatment as per Dr Liebowitz. What I'm lookng for is some guidance as what to suggest. That's why I was looking at Dr Liebowitz's protocol and what in his arsenal whould be appropriate for me. I am currently betrween cycles and on Avodart. I would expect to go back on Lupron when psa hits 6.
Whatever advice you can give would be appreciated.
Thanks.
Ed Roge
At 11:14pm on June 24th, 2008, Kathy Meade said…
Gee Ralph don't think cats get prostate cancer but dogs do. :-) I have dog pictures if you want one. BTW great cat.
At 5:46pm on June 24th, 2008, Patricia Suarez said…
Dear Mr. Valle,

Your discussions are of interest to me. Especially the discussion about "The use of combined therapies..." Is there anyway you could explain in layman terms? When I read your bio I was not surprised your were a chemist!
At 4:19pm on June 24th, 2008, edward roge said…
Ralph
Are you familiar with Dr Leibowitz's different treatment approaches and what is your thoughts about them?
Thanks
Ed Roge eroge@optonline.net
At 2:16pm on June 24th, 2008, Angela Jenkins said…
Just wanted to say, the discussion you started about screening has been the most interesting, informative, and active of any to date. Boy, have I learned a lot! I appreciate all the experience and wisdom that you bring to this network.
At 3:40pm on June 11th, 2008, Mike said…
Thanks Ralph. Rick Ward let me know that these data came from a 2007 ACS report. I adjusted the blog accordingly (as you may have noted already).
At 6:04am on April 24th, 2008, John E. Holliday, FACMPE said…
Thanks Ralph, my friend, any time I am with you, I am in good company. - John (aka) az4peaks@newPCa.org
At 1:08pm on April 19th, 2008, Rick Ward said…
Don't think so, Ralph. The halving of PSA expression is consistent for all three groups according to the literature I read. To track a patient being treated with finasteride for PCa the PSA still needs to be doubled to compare with the pre-finasteride values. Yes, the PSA will track success/failure, but not as a raw figure on a timeline.
At 11:53am on April 19th, 2008, Rick Ward said…
Ralph, in your comment about finasteride it might have been helpful to point out that in the literature it is common to double the PSA to compare to non-finasteride PSA. Finasteride has been found to decrease by about 50% the PSA expression with no attendant alteration in the apparent PCa status or characteristics.

Rick
At 11:14pm on April 18th, 2008, Kathy Meade said…
Ralph,

I know you posted an item about screening, or maybe I dreamed it, but i can't find it now. Where was it posted?
 
 

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